Hydroxamic Acids and Hydroxyazine Heterocycles
نویسندگان
چکیده
منابع مشابه
Catalytic Kinetic Resolution of Saturated N-Heterocycles by Enantioselective Amidation with Chiral Hydroxamic Acids.
The preparation of enantioenriched chiral compounds by kinetic resolution dates back to the laboratories of Louis Pasteur in the middle of the 19th century. Unlike asymmetric synthesis, this process can always deliver enantiopure material (ee > 99%) if the reactions are allowed to proceed to sufficient conversion and the selectivity of the process is not unity (s > 1). One of the most appealing...
متن کاملTheoretical Studies on Hydroxamic Acids
Hydroxamic acids find many applications in chemistry and biology and have been the subject of many experimental investigations. Theoretical studies are not as frequent. However, the smallest homolog, formohydroxamic acid (FHA), has been studied at various levels, including high-level ab initio and density functional with large basis sets. All studies indicate that it exists as the Z-amide tauto...
متن کاملChemistry and Biology of Hydroxamic Acids
The action of salicylhydroxamic acid and its halogen derivatives against tuberculosis, fungi, trypanosomae, and the biosynthesis of cholesterol are described. Their hypoglycemic and phospholipid lowering actions are also mentioned. The author suggested, in 1948, the use of salicylhydroxamic acid I (X = Y = Z = R = H)—called SH—as an antitubercular agent [26]. The suggestion was based on the hyp...
متن کاملMutagenicity and antibacterial activity of hydroxamic acids.
Hydroxamic acids demonstrated mutagenic and antibacterial activities. These activities appear to be dependent on the hydroxamic acid function and are probably due to the interaction with deoxyribonucleic acid.
متن کاملAnalysis of hydroxamic acids and hydrazides; preparation and properties of dinitrophenyl derivatives of hydroxamic acids, oximes, hydrazides, and hydrazones.
The cleavage of gelatin to smaller molecular units by aqueous hydroxylamine or hydrazine under relatively mild conditions of temperature and pH has suggested the existence of “ester-like” or imide linkages in this protein (1). The amide bonds of gelatin were cleaved only to a minor extent and could not account for the large change in molecular weight. It is known, however, that prolonged treatm...
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ژورنال
عنوان ژورنال: Oleoscience
سال: 2001
ISSN: 1345-8949
DOI: 10.5650/oleoscience.1.599